Generic tadalafil: identical molecule, different cost

Free bonus

The price gap is accounting, not chemistry

The usual worry about generics is that something must have been cut. With a medicine, that is not how it works. Same active ingredient, same amount, same form. The price difference exists because the original development costs were recovered long ago. Without prescription, plain packaging.

Cialis

Select dosage:

Cialis 10mg Price
Product	Quantity	Per Unit	Price
Cialis - 10mg	10 pill	£2.50	£27.78 £25.00 −10% 🎁 +4 bonus
Cialis - 10mg	20 pill	£2.25	£50.00 £45.00 −10% 🎁 +4 bonus
Cialis - 10mg	30 pill	£2.07	£68.89 £62.00 −10% 🎁 +4 bonus
Cialis - 10mg	60 pill	£1.95	£130.00 £117.00 −10% 🎁 +4 bonus
Cialis - 10mg	90 pill	£1.57	£156.67 £141.00 −10% 🎁 +10 bonus
Cialis - 10mg	120 pill	£1.31	£174.44 £157.00 −10% 🎁 +10 bonus
Cialis - 10mg	180 pill	£0.98	£196.67 £177.00 −10% 🎁 +10 bonus
Cialis - 10mg	270 pill	£0.89	£265.56 £239.00 −10% 🎁 +10 bonus
Cialis - 10mg	360 pill	£0.80	£318.89 £287.00 −10% 🎁 +10 bonus

Cialis 20mg Price
Product	Quantity	Per Unit	Price
Cialis - 20mg	10 pill	£2.70	£30.00 £27.00 −10% 🎁 +4 bonus
Cialis - 20mg	20 pill	£2.35	£52.22 £47.00 −10% 🎁 +4 bonus
Cialis - 20mg	30 pill	£2.13	£71.11 £64.00 −10% 🎁 +4 bonus
Cialis - 20mg	60 pill	£2.05	£136.67 £123.00 −10% 🎁 +4 bonus
Cialis - 20mg	90 pill	£1.71	£171.11 £154.00 −10% 🎁 +10 bonus
Cialis - 20mg	120 pill	£1.44	£192.22 £173.00 −10% 🎁 +10 bonus
Cialis - 20mg	180 pill	£1.24	£247.78 £223.00 −10% 🎁 +10 bonus
Cialis - 20mg	270 pill	£0.98	£293.33 £264.00 −10% 🎁 +10 bonus
Cialis - 20mg	360 pill	£0.88	£351.11 £316.00 −10% 🎁 +10 bonus

Cialis 40mg Price
Product	Quantity	Per Unit	Price
Cialis - 40mg	10 pill	£2.90	£32.22 £29.00 −10% 🎁 +4 bonus
Cialis - 40mg	20 pill	£2.55	£56.67 £51.00 −10% 🎁 +4 bonus
Cialis - 40mg	30 pill	£2.23	£74.44 £67.00 −10% 🎁 +4 bonus
Cialis - 40mg	60 pill	£2.08	£138.89 £125.00 −10% 🎁 +4 bonus
Cialis - 40mg	90 pill	£1.78	£177.78 £160.00 −10% 🎁 +10 bonus
Cialis - 40mg	120 pill	£1.57	£208.89 £188.00 −10% 🎁 +10 bonus
Cialis - 40mg	180 pill	£1.29	£258.89 £233.00 −10% 🎁 +10 bonus
Cialis - 40mg	270 pill	£1.17	£351.11 £316.00 −10% 🎁 +10 bonus
Cialis - 40mg	360 pill	£1.03	£411.11 £370.00 −10% 🎁 +10 bonus

Cialis 60mg Price
Product	Quantity	Per Unit	Price
Cialis - 60mg	10 pill	£3.10	£34.44 £31.00 −10% 🎁 +4 bonus
Cialis - 60mg	20 pill	£2.80	£62.22 £56.00 −10% 🎁 +4 bonus
Cialis - 60mg	30 pill	£2.40	£80.00 £72.00 −10% 🎁 +4 bonus
Cialis - 60mg	60 pill	£2.22	£147.78 £133.00 −10% 🎁 +4 bonus
Cialis - 60mg	90 pill	£1.93	£193.33 £174.00 −10% 🎁 +10 bonus
Cialis - 60mg	120 pill	£1.59	£212.22 £191.00 −10% 🎁 +10 bonus
Cialis - 60mg	180 pill	£1.36	£272.22 £245.00 −10% 🎁 +10 bonus
Cialis - 60mg	270 pill	£1.22	£366.67 £330.00 −10% 🎁 +10 bonus
Cialis - 60mg	360 pill	£1.07	£427.78 £385.00 −10% 🎁 +10 bonus

Cialis 80mg Price
Product	Quantity	Per Unit	Price
Cialis - 80mg	10 pill	£4.20	£46.67 £42.00 −10% 🎁 +4 bonus
Cialis - 80mg	20 pill	£3.65	£81.11 £73.00 −10% 🎁 +4 bonus
Cialis - 80mg	30 pill	£3.37	£112.22 £101.00 −10% 🎁 +4 bonus
Cialis - 80mg	60 pill	£3.15	£210.00 £189.00 −10% 🎁 +4 bonus
Cialis - 80mg	90 pill	£2.87	£286.67 £258.00 −10% 🎁 +10 bonus
Cialis - 80mg	120 pill	£2.61	£347.78 £313.00 −10% 🎁 +10 bonus

How does the free pills bonus work?

With every order of this product you receive free pills. You choose the exact variant at checkout.

Up to 89 pills per pack: 4 Viagra or 4 Cialis or 2 Levitra — your choice.
From 90 pills per pack: 10 Viagra or 10 Cialis or 4 Levitra — your choice.

The bonus is applied automatically at checkout.

Description
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What does a generic have to demonstrate?

A generic is not an approximation. Before it can be sold, it has to show that it delivers a comparable amount of the active compound into the bloodstream over a comparable time course.

Same active ingredient, same strength, same route of administration.

What may differ: the binders and fillers, the colour, the shape, the coating, the name on the box.

The price gap comes from the development costs having already been paid. A new medicine takes enormous investment to bring to market, and that is recovered during the patent period. Once the patent lapses, other manufacturers can produce the same compound without repeating it.

What you get with tadalafil specifically

The main thing is duration. This molecule stays active far longer than the others in the class — a window well beyond a day rather than a handful of hours.

That removes the clock-watching. You are not taking a tablet an hour ahead and hoping the evening unfolds on schedule.

The second advantage is that food barely affects it. Sildenafil is noticeably slowed by a heavy meal; tadalafil largely is not.

Together those two properties are why many men prefer it, and why the generic version is bought in quantity.

The mechanism

Arousal causes nitric oxide release in the erectile tissue. That triggers a messenger molecule which relaxes the smooth muscle of the small arteries.

Relaxed arteries admit blood. The engorged tissue compresses the draining veins so the blood stays in place.

PDE5 destroys that messenger and the erection resolves. Tadalafil blocks PDE5, extending how long the messenger survives.

The requirement for arousal does not go away. No arousal, no nitric oxide, no messenger, nothing to preserve.

Two ways it is used

As needed. A larger dose before an occasion, with a long window afterwards. Suits people who do not need cover every day.

Low dose daily. A small amount every day, producing a constant background level and no timing at all. Suits people who want complete spontaneity, or who also have prostate symptoms.

The daily approach costs more in tablets but removes the planning entirely. Which suits better depends on how often it is actually needed.

Taking it

Thirty minutes to an hour before, for the as-needed approach.
Food makes little difference.
Once in twenty-four hours.
Moderate alcohol at most.
No grapefruit juice.

Nitrates: the one hard stop

This is the single line on the page with no room for interpretation.

Glyceryl trinitrate, isosorbide mononitrate, isosorbide dinitrate, nicorandil — anything taken for angina, including the spray carried for emergencies.

Together they can drop blood pressure to a dangerous level. Not mild dizziness. Circulatory collapse.

The same applies to amyl nitrite used recreationally, sold as poppers.

And with tadalafil there is an extra consideration: it stays in the body far longer than the others. A gap of a day or two is not enough. If you take nitrates in any form, this is out entirely.

Who should not take it

Recent heart attack or stroke
Unstable angina, or chest pain on light exertion
Severe heart failure
Uncontrolled high blood pressure, or markedly low blood pressure
Severe liver or kidney disease
Retinitis pigmentosa
Previous sudden vision loss from reduced optic nerve blood supply

Alpha blockers for an enlarged prostate lower blood pressure as well, and the effects add. That pairing needs arranging deliberately.

The back ache, and where it comes from

Back and muscle ache turns up more with tadalafil than with the alternatives, and there is a reason.

These drugs block PDE5, but none of them does so perfectly. Tadalafil also has some effect on a related enzyme, PDE11, found in skeletal muscle.

That is the leading explanation for the aching lower back and thighs some men notice, typically starting a day or so after taking it.

It is harmless and it passes. An ordinary painkiller handles it. For some people a lower strength avoids it while keeping most of the effect.

Other possible side effects

Headache
Indigestion, reflux
Flushing
Blocked nose
Limb pain
Dizziness

Two things that need help immediately

An erection lasting more than four hours. Not something to wait out — after several hours the tissue begins to sustain permanent damage.

Sudden loss of vision or hearing, one side or both. Stop and get seen urgently.

Both rare. Both measured in hours, not days.

Ordering without prescription: how it works

Generic pricing is exactly why people tend to buy a proper supply rather than a handful.

Pick the strength and the pack size, put in a delivery address, confirm. Couple of minutes, any time of day, no queue and no conversation across a counter.

It goes out in plain packaging. No pharmacy name on the outside, nothing that hints at what is inside. How long delivery takes depends on where the parcel is headed.

On price it comes down to strength and pack size. Larger packs generaly work out better per unit.

If something arrives damaged anywhere in the UK, send the order number and a photograph the same day. We replace free of charge or refund in pounds. Do not use medication from a damaged blister.